More information has emerged about the impact of the updates, including the issues being caused to IIS and SQL Server, the bedrock of most web-based systems.
In particular, for Alpha Tracker asbestos software users, you may find that servers which have had the updates applied do not allow you to log in or may only run for a few minutes before having an issue. The solution is to get the Windows Updates uninstalled for now and tell the server not to install them again. Our support desk can give you more specific information if you need it.
Microsoft is working on a solution and you can read more information here: https://support.microsoft.com/en-nz/help/4338815/windows-81-update-kb4338815